ECM Serum

ECM Serum – Taking our nature meets science to the next level.

A revolutionary, multifunctional serum that helps reconstruct the Extra Cellular Matrix.  Promotes cellular resistance to oxidative stress.  Prevents degradation of essential ECM proteins and inhibits one of the skins pro-inflammatory pathways.

Reduces productions of MMP’s – Most people have never heard of matrix metalloproteinases (or, MMPs). Yet, these substances are enzymes that can have a significant, lasting impact on your skin. MMPs work by chipping away at the structural integrity of your skin causing the deterioration of collagen, elastin, and other proteins.

Activates the transcription factor that intern, activates the skins antioxidant response.

Anchors epidermis to dermis for structural support.

Anchors cells to ECM for cell adhesion.

Ingredients:

Sodium Hyaluronate, Peptide and Amino Acid Complex, Avocado Peptides, Natural Vitamin A Oil, Squalane Oil, Plant Growth Factors, Mushroom Extracts, Hydrolyzed Proteins, Broccoli Seed Oil, Olive Oil Esters, Natural Moisturizing Factors, Caprylyl/Capryl Glucoside, Marine Fermented Extracts, Lecithin Extracts, Avocado Extracts, Potassium Sorbate and Hydrosols.

Natural Moisturizing Factors (NMF) including Sodium PCA, Wheat Amino Acids (rich in proline), Glycerin, Sodium Hyaluronate and Hydroxyproline.  This unique ratio of ingredients provides superior performance while delivering a better feel and improving formulation aesthetics. 

Superior Water Retention Proline and hydroxyproline are excellent moisturizers with the highest water holding capacity of all amino acids.  Sodium PCA is a super moisturizer, compared to other humectants it has the highest in vitro water binding capacity. Sodium Hyaluronate can hold 1000x its weight in water. Provitamin B5 (panthenol) supports barrier health and helps lock in moisture.

Nourishing to Support Skin Health Panthenol restores collagen and smooths skin, Wheat Amino Acids nourish and soothe dry skin.

Features:

• Mimetic to skin’s Natural Moisturizing Factors
• Comprehensive moisturizer
• Contains wholesome amino acids and provitamin B5.
• Free from gluten, parabens, and harsh solvent systems

Advantages

• Restores hydration.
• Supports skin barrier function.
• Optimized solutions deliver better aesthetics.

Benefits

• Delivers immediate and intense long term moisturization.
• Skin instantly feels smoother and better moisturized.
• Nourished to promote overall skin health.
• Soothes dry skin.

Growth Factors – Any of a group of proteins that stimulate the growth of specific tissues. Growth factors play an important role in promoting cellular differentiation and cell division, and they occur in a wide range of organisms, including insects, amphibians, humans, and plants.  Dermaki chooses to find growth factors that occur naturally in nature, so we get ours from plants.  There is lots of research that is controversial overusing human growth factors over plants.  We saw that human growth factors can be stronger than plants, but we make up the difference with peptides and amino acids.  This allows us to keep up with the strength of human growth factors yet stay true to nature.

Boost production of key components at the DEJ for maximal reduction of fine lines and wrinkles.

Peptides and Peptide Complex

Peptide complexes are compounds that are designed to make use of a chain of amino acids to create and release protein to nourish the skin. These products are effective for anti-aging giving you results that are equal to that of plastic surgery over extended periods of time. There is evidence that a good quality peptide complex can be helpful in keeping the skin properly moisturized and thus looking younger that it would otherwise.

Peptides – Protein comprised of long segments of amino acids arranged like a chain. When collagen breaks down, short segments of amino acids are formed (tiny proteins and active molecules know and peptides), which can provide significant anti-aging and acne benefits.

Peptide Complex – Anti-aging, anti-wrinkle and skin-regenerating properties improving the appearance of aging skin, firmness, and fines lines/wrinkles. This is a cocktail of multiple is ingredients.

Pseudoalteromonas Ferment Extract, also known as Antarcticine or GPS, is a unique ingredient commonly found in skincare and cosmetic products. It’s derived from the fermentation of the bacterium Pseudoalteromonas, which thrives in cold oceanic waters, particularly in the Antarctic.

Here’s how it works:

Hydration: Pseudoalteromonas Ferment Extract acts as a humectant, helping your skin retain moisture. It’s especially beneficial for dry or dehydrated skin.

Skin Health Support: By providing hydration, this extract contributes to overall skin health. It’s often used in concentrations ranging from 1% to 5% within cosmetic formulations.

In summary, this ingredient helps keep your skin hydrated and healthy, making it suitable for various skin types, including dry and sensitive skin.

Mushroom Extracts – contains snow and shiitake mushroom-based extract that prevents collagen deterioration and improves the structure, organization, and quality of collagen, all of which are associated with a firmer, smoother complexion. 

As we age, the amount of collagen in our skin decreases and enzymes like matrix metalloproteinases (MMPs) increase, leading to signs of aging such as roughness or reduction of firmness. Behaves as a strong antioxidant that reduces the damage by reactive oxygen species (ROS) as well as lipid peroxidation. It assists with type I collagen synthesis and boosts PLOD1 levels, which contributes to protein quality, while reducing carbonylation, the degradation of protein, which “may be considered a hallmark of aging”. 

Key Benefits

• Promotes firmer appearance of face, neck, and décolleté.
• Boosts the synthesis of collagen.
• Reduces the deterioration of collagen.
• Improves the quality of collagen.
• Prevents the degradation of matrix proteins, like collagen and elastin.
• Behaves as an antioxidant.