A True Professional Skincare Line

Professional Wholesale Overview

Barrier-First Science | Professional Integrity | Proven Results

Dermaki Skincare is a professional-only, science-driven skincare line rooted in corneotherapy and barrier health.
Our formulations are designed exclusively for licensed professionals who value results, integrity, and long-term skin health.

Not retail. Not trend-driven. Not diluted.
Dermaki is skincare for professionals who practice with purpose.

WHAT DEFINES A TRUE PROFESSIONAL LINE

Professional Skincare Is Defined By:

• Professional-only distribution

• Clinically relevant concentrations of actives

• Evidence-based formulation

• Consistency in manufacturing

• Education and practitioner support

• Ethical and transparent sourcing

Dermaki does not sell directly to consumers.
We honor the education, expertise, and trust of licensed professionals.

FORMULATION STANDARDS

Science Without Compromise

Dermaki formulations are developed using:

• Pharmaceutical-grade active ingredients

• Biomimetic lipids and humectants

• Clinically supported actives

• No unnecessary fillers or fragrance

Every formula is produced with batch-to-batch consistency, ensuring predictable, professional results.

PROFESSIONAL-ENDORSED USE

Recommended by Licensed Professionals

Dermaki is recommended by:

• Estheticians

• Dermatologists

• Medical spas

• Oncology support providers

• General practitioners

• Chiropractors, massage therapists & podiatrists

Common use cases include:

• Barrier-compromised skin

• Post-procedure recovery

• Inflammation-prone skin

• Acne-prone and sensitized skin

• Dry, calloused, or environmentally stressed skin

Products are cosmetic in nature and not intended to diagnose, treat, or cure disease.

GLOBAL QUALITY STANDARDS

Certified Manufacturing Excellence

Ingredients and manufacturing partners meet or exceed:

• ISO 9001

• GMP

• HACCP

• HALAL

• Kosher

We prioritize:

• Organic & non-GMO sourcing

• Sustainable, ethical suppliers

• Transparent ingredient disclosure

WHOLESALE PARTNERSHIP

Why Professionals Choose Dermaki

• No retail competition

• Predictable clinical results

• Barrier-safe protocols

• Education & formulation transparency

• Responsive, knowledgeable support

We succeed when you succeed.

CLINICAL PHILOSOPHY

Barrier-First. Biology-Respecting. Results-Driven.

Dermaki is rooted in corneotherapy, prioritizing the health and integrity of the stratum corneum as the foundation of all skin correction.

We reject aggressive, inflammatory protocols in favor of:

• Skin barrier restoration

• Inflammation prevention

• Biomimetic repair

• Long-term skin resilience

Healthy skin performs better—and ages better.

SKIN SENSORY & CLINICAL COMPLIANCE

Why How a Product Feels Matters

Skin is a neuro-immuno-endocrine organ.
Overstimulation compromises barrier integrity and client compliance.

Dermaki formulations respect:

• Sensory nerve signaling

• Barrier perception (no burning, stinging, stripping)

• Consistent client usage

Comfort is not cosmetic—it is clinical.

CLEAN, ETHICAL FORMULATION

Ingredient Integrity You Can Trust

Dermaki products are:

• Vegan-friendly (clearly disclosed exceptions)

• Cruelty-free

• Free from:

  • Parabens

  • Mineral oil & petroleum

  • Propylene glycol

  • SLS/SLES

  • Harsh fragrances & dyes

Therapeutic-grade essential oils are used only when appropriate and are third-party tested for purity.

SUSTAINABILITY & RESPONSIBILITY

Skin Health Without Environmental Cost

Dermaki is committed to:

• Sustainable ingredient sourcing

• Eco-conscious production practices

• Responsible global distribution partnerships

Beautiful skin should never come at the Earth’s expense.

BARRIER REPAIR SYSTEM

How Dermaki Supports Skin Recovery

SUPPORT & CONTACT

Dermaki’s Caring Team

We are committed to exceptional service and professional partnership.

📞 (208) 691.0158
🕘 Monday–Friday | 8 AM–5 PM PST

Dealer inquiries, education support, and product guidance are available.

Endorsed by Professionals

Dermaki products are recommended by dermatologists, estheticians, medical spas, oncologists, general practitioners, chiropractors, massage therapists and podiatrists for a range of conditions. These include dermatitis, eczema, and psoriasis, as well as calloused and dry skin resulting from work conditions, lifestyle, aging, acne, and sensitive skin.

• Our products have not been evaluated by the FDA and not intended to cure or treat diseases.

1. Neurosensory Feedback

The skin is a neuro-immuno-endocrine organ loaded with sensory receptors. These receptors respond to external stimuli—temperature, texture, and even certain chemical compounds—sending messages to the brain and triggering physiological responses. Some skincare ingredients can influence:

• Sensory nerves (e.g., menthol or capsaicin),

• Inflammatory response (e.g., histamine release),

• Barrier perception (tightness vs. suppleness).

2. Formulation Acceptance

Sensory characteristics such as texture, spread ability, absorption rate, and after-feel affect whether clients will continue using a product consistently. Even the best ingredients won’t deliver benefits if the user finds the experience unpleasant.

3. Therapeutic Signals

Certain ingredients signal to the skin through sensory pathways to activate repair or anti-inflammatory responses. For example:

• Niacinamide may cause temporary tingling as vasodilation improves microcirculation.

• Essential fatty acids can reduce sensory irritation by restoring barrier function.

4. Corneotherapy Implications

From a chronotherapeutic standpoint, respecting the skin’s natural sensory and barrier functions is essential. If a product overstimulates the skin (e.g., stinging, burning, or dryness), it may compromise barrier integrity—even if it contains beneficial actives.

5. Psychological Impact

Pleasant skin sensory experiences contribute to a sense of well-being and ritual, reinforcing positive emotional associations with skincare routines. This can support skin homeostasis via the skin-brain connection.

In summary, skin sensory matters not just for comfort, but for barrier integrity, compliance, neurocutaneous health, and the overall success of a skincare regimen.

We are proud to be a partner to professionals who want science without sacrifice—and skin results with integrity.

We believe in providing the best skincare products at Dermaki. Vegan-friendly, our range is free of parabens, animal by-products, mineral oils, petroleum, propylene glycol, sodium lauryl sulfates, harmful colorants and fragrances, and other harsh cosmetic chemicals. Dermaki’s moisturizers are so gentle that they can be used on the face as well as the body. We only use therapeutic-grade essential oils obtained from organically grown aromatic plants that have been third party tested to be pure and to guarantee the highest quality. 

We only use the highest quality ingredients that are certified by the best standards in the world: ISO 9001, GMP, HACCP, HALAL and Kosher.  We also only use ingredients that are sustainable, ethical and transparent.  We want you to know you are getting the best because you deserve to only be putting the best on your skin.  We strive to always source organic and Non-GMO, Gluten-Free, grown without pesticides, no sulphates/parabens or antibiotics.  Dermaki Skincare does not test on animals and is against unnecessary, repeated or senseless animal testing. We are committed to partnering with organizations who also meet these guidelines.

Clinical Philosophy

At Dermaki Skincare, our clinical philosophy is rooted in corneotherapy, a progressive skin treatment methodology that prioritizes the health and integrity of the skin barrier. We believe that true skin transformation begins with understanding the physiology and histology of the skin—then working with, not against, its natural functions.

Our formulations are driven by:

• Barrier-first strategies that prevent inflammation and restore skin resilience

• Biomimetic ingredients that mirror the skin’s own components to support regeneration

• Pharmaceutical-grade actives for targeted results without irritation

• Purity and potency—no unnecessary fillers, no fragrance, no compromise

Dermaki rejects the outdated notion of aggressive peels, over-exfoliation, and inflammatory protocols. Instead, we promote informed, evidence-based treatment plans tailored to the individual, not the trend.

Whether you’re treating chronic inflammation, post-procedure recovery, acne-prone skin, or visible aging, Dermaki is designed to protect, correct, and support long-term skin health.

Skin sensory—how the skin feels and perceives products—is a crucial but often underappreciated aspect of skincare formulation. It plays a significant role in both the effectiveness and user experience of a product. Here’s why it’s important:

Made for Health and Well-being

We Care About the Earth 

At Dermaki, sustainability is at the core of our mission. We work closely with our distributors to ensure that our ingredients are ethically and responsibly sourced, prioritizing sustainability, fairness, and respect for the planet’s resources.

Our commitment to environmental responsibility drives us to minimize our ecological footprint through:
Sustainable ingredient sourcing
Eco-conscious production practices
Responsible global partnerships

By making mindful choices, we protect and preserve the health of our planet—because beautiful skin shouldn’t come at the Earth’s expense. 

We Strive to Try and Use As Much Plant-Based Ingredients We Can & Are Always Cruelty-Free

We’re committed to providing ethical, skincare that is kind to both animals and the environment. Our products are never tested on animals and very few products have any animal by products.  A few exceptions would be Lip Balm has beeswax, and Advanced Dermal Complex has Emu Oil.  Your customers can feel good about the choices they make for their skin.

Dermaki’s Caring Team

At Dermaki, our customers are at the heart of everything we do. We are committed to providing exceptional customer service and ensuring that every interaction with us is positive, supportive, and fulfilling.

Whether you have questions about our products, need personalized skincare guidance, or simply want to share your experience, we’re here to help.

 Feel free to email or text us anytime, and we’ll respond as quickly as possible.
 Our support team is available Monday–Friday, 8 AM to 5 PM PST.

Your skincare journey matters to us, and we’re honored to be a part of it! 

Smart Skincare, Backed by Science

Your skin deserves pure, effective, and responsibly formulated ingredients that support a healthy complexion. Trust Dermaki for skincare that is as transparent as it is transformative.

Barrier First = Separation of Functions

Healthy skin requires:

• Water (humectants)

• Lipids (barrier repair)

• Actives (correction)

• Anti-inflammatory signaling

All-in-one formulas often:

• Compromise stability of ingredients

• Require stronger preservatives

• Limit active potency

• Blend incompatible pH systems

Layering keeps:

• Actives stable

• pH optimized

• Lipids intact

• Formulas flexible

This is aligned with corneotherapy principles.

Professional-Level Customization

In a treatment room:

• Acne client + winter dryness ≠ same formula as acne client in summer.

• Pigmented client with inflammation ≠ pigment-only client.

• Oncology-safe ≠ standard anti-aging.

Layering allows you to:

• Mix for the moment.

• Treat what’s present.

• Protect what’s vulnerable.

That’s professional skincare — not cosmetic marketing.

The Corneotherapy Perspective

Corneotherapy teaches:

• Correct the barrier first.

• Then normalize function.

• Then treat the condition.

• Avoid overstimulation.

Layering respects skin physiology.

All-in-one formulas often respect marketing convenience.

Why Layer Instead of Using an All-in-One Formula?

Skin Is Dynamic — Not Static

Skin changes:

• Morning vs evening

• Summer vs winter

• Inflamed vs calm

• Post-treatment vs maintenance

An all-in-one formula assumes the skin needs the same ratios of actives, lipids, humectants, and antioxidants every day.

Layering allows:

• Adjustment of strength

• Adjustment of frequency

• Adjustment of delivery method

• Adjustment based on barrier status

That’s intelligent skincare — not fixed skincare.

Precision Dosing of Actives

In an all-in-one product:

• Actives are locked at a fixed percentage.

• You cannot reduce vitamin A if skin becomes reactive.

• You cannot increase brightening when pigmentation flares.

• You cannot remove exfoliation when the barrier is compromised.

With layering:

• You can rotate actives.

• You can buffer actives with lipid support.

• You can apply every other day instead of daily.

• You can remove a step temporarily without abandoning the whole system.

This prevents chronic micro-inflammation — a major contributor to aging and pigmentation.

Better Absorption & Penetration Control

When you layer:

• You control the order (water-based → active → lipid seal)

• You can use toners to distribute actives evenly

• You can adjust occlusion

• You can use modality (ultrasound, massage, LED)

An all-in-one product cannot adjust penetration depth.

Reduced Risk of Over-Stimulation

Many “all-in-one” formulas combine:

• Vitamin A

• Vitamin C

• Exfoliating acids

• Peptides

• Brighteners

• Anti-inflammatory agents

That sounds appealing — but:

• Skin may not need all of them at once.

• Chronic daily exposure can weaken the barrier.

• Sensitive clients cannot tolerate fixed blends.

Layering allows:

• Rest days

• Recovery blends

• Post-procedure modifications

• Age-specific adjustments

When Are All-in-One Formulas Useful?

They can be appropriate for:

• Simple routines

• Entry-level consumers

• Travel

• Maintenance phases

But they are rarely ideal for:

• Barrier-compromised skin

• Aging with inflammation

• Pigmentation-prone skin

• Acne with sensitivity

• Post-procedure care